Enemies consist of different types of ants such as the big headed ant, red fire ants, thief ants, ghost ants, meat ants,  red carpenter ants, and the crazy ant.

Bosses:

Dinoponera - Dinoponera have a total body length of 3–4 cm (1.2–1.6 in), making them one of the world's biggest ants. Dino has a stinger that injects a significant amount of venom into its prey. Be wary of its venomous sting.

Colonies - Colonies vary in size depending on the species, but they usually have less than 100 members. Enemy queen is protected by its soldier ants but sometimes you can find her alone.

Giant Spider - Because of its long legs, it can dodge quickly, making it difficult to hit. It scatters webs on the floor and throws some at you, which can trap you and slow you down for a short period of time.

Antlion - Uses its wings to fly and slash the enemy. Attempt to evade its hits. Usually it rest after a flight.